The Augmentarium facilitates a number of distinct and tangible advances for research, education, and training. Projects are drawn from the sciences, engineering, and medicine, and will take advantage of the unique capabilities of the Augmentarium. The applications include large-scale visualization for astronomy datasets, modeling of climate and weather instabilities, stem-cells and regenerative medicine, and cybersecurity, in addition to fundamental advances in the design and deployment of next-generation visualization environments.